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1 GSH is an important antioxidant and plays a major role in the detoxification of endogenous metabolic products, including lipid peroxides, and xenobiotic compounds including pollutants, heavy metals, and drugs
The main metabolic pathway is the formation of paraxanthine (17-X) followed by N7-demethylation, reactions via CYP1A2 (80% of the total amount), and then oxidation under the action of XO with the formation of 1-methyluric acid (1U)
Is intravenous glutathione more effective than oral forms
This decrease can be accelerated by environmental factors such as pollution, UV exposure, and lifestyle choices
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